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Amasheh, M., Andres, S., Amasheh, S., Fromm, M

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However, unlike apoptotic cells, which are permanently eliminated, senescent cells can prevail for prolonged periods of time and accumulate with age(Krishnamurthy et al., 2004)

Pyrazole-triazole hybrid analogs as selective cyclooxygenases-2 (COX-2) inhibitors with cardioprotective effects As previously discussed, the sulfonyl/sulfonamide motif is a characteristic pharmacophore group for selective COX-2 inhibition