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In recent years, alternative mechanisms of nilotinib have been discovered, such inactivation of p38 MAPK in microglial/astroglial cells and a myoblast cell line 175 , 176 , inhibition of the discoidin domain receptor (DDR) in metastatic colorectal cancer cells 177 , and prevention of NF-B activation in microglial cells 178 indicating there are more target points of nilotinib

Tang et al