glp-1 vs glp-2 differences what is the difference between glp 1 and gip Dual GIP/GLP-1 receptor agonists: New advances for treating type-2 diabetes GLP-1 vs GLP-2 vs GLP-3:

*Correspondence: Baptist Gallwitz [email protected] This article was submitted to Molecular and Structural Endocrinology, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Reflux is a common, manageable side effect of GLP-1 therapy, not an indication of inadequate tolerance or a contraindication to continuing

Seek urgent medical attention (contact 999, NHS 111, or attend A&E) if you experience: Black, tarry stools (melaena) may indicate upper gastrointestinal bleeding Bright red blood in or on stools, particularly if accompanied by dizziness, weakness, or rapid heartbeat Pale or clay-coloured stools with yellowing of skin or eyes (jaundice) potential biliary obstruction or liver dysfunction Severe abdominal pain with stool changes, especially if persistent or worsening Stop your GLP-1 medication and seek urgent medical assessment if you develop symptoms suggestive of pancreatitis (severe, persistent abdominal pain which may radiate to your back, with or without vomiting)

Aminian et al., 2020

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PYY infusion in humans had limited effects on plasma glucose, insulin or glucagon levels on its own (128, 137), nor did it affect glucose excursion and insulin levels during intravenous (138) or oral glucose challenge (136)