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The clinical manifestations of ALS usually appear between 5060 years of age, suggesting that neurons die through cumulative damage to normal cellular processes

In severe cases, individuals may experience visual disturbances or more profound neuropsychiatric symptoms

Billing for wasted medication is submitted with the same J-code on a second line and with a -JW modifier

10.1016/S0893-133X(00)00208-6 24

Significant brain alterations in pain-processing areas, abnormal pain modulation, central sensitization, cortical hyperexcitability, neurogenic inflammation, and ongoing neuroinflammation are central to the development and persistence of chronic migraines (35)