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10.1038/srep06767 6 BaiL

Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins

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TCA-CYCLE INTERMEDIATES GENERATE CYTOSOLIC AND MITOCHONDRIAL NADPH Isocitrate and malate are two TCA-cycle metabolites that generate NADPH through mitochondrial and cytosolic forms of isocitrate dehydrogenases (IDH1 and IDH2) and malic enzymes (ME1 and ME3), respectively

For longterm storage (months to years), deep freezing at ~80C (112F) is recommended