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Olea europaea leaf extract up-regulates Nrf2/ARE/HO-1 signaling and attenuates cyclophosphamide-induced oxidative stress, inflammation and apoptosis in rat kidney

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Based on this, an investigator-initiated, phase III, double-blind, randomized controlled trial was performed to evaluate the efficacy and safety of high-dose selenium (2000 g/day) intravenously in a 1:1 ratio for the prevention of CIPN in 68 platinum-sensitive cancer patients treated with paclitaxel, carboplatin, and bevacizumab [110]

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Ectopic expression of OspC effectors promotes ADP-riboxanation of septins in host cells Considering that proteins identified in our ADP-ribosylome datasets are not necessarily modified (i.e., they may be enriched due to interaction with bona fide ADP-riboxanated substrates), we next sought to determine exactly which septins are post-translationally modified by OspC effectors

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