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The role of ABC transporters in drug resistance, metabolism and toxicity

Kisspeptin The Upstream Hormonal Cascade Trigger Kisspeptin (Kiss1 peptide) is a hypothalamic neuropeptide that activates KISS1R (GPR54) receptors on gonadotropin-releasing hormone (GnRH) neurons making it the master upstream regulator of the entire reproductive hormonal axis

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Their shared belief is that the richness of neuronal interactions in corticothalamic systems is crucial for achieving consciousness

For example, celecoxib nanoparticles, formulated with ethyl cellulose and sodium caseinate, demonstrated rapid absorption and greater systemic exposure

Dysfunction of glutamatergic neurotransmission is a core feature of stress-related disorders, including MDD [27,28,29]