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The only exception was the conventional Neuromax B12 formulation, which led to significant changes in certain renal function parameters, such as serum levels of sodium, potassium, chloride, and bicarbonate, as well as in some hematological parameters, including the relative abundance of monocytes and basophils

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J Invest Dermatol 120:542547 Nishijima C, Hayakawa I, Matsushita T, Komura K, Hasegawa M, Takehara K, Sato S (2004) Autoantibody against matrix metalloproteinase-3 in patients with systemic sclerosis

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