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Presuming that the putative high-folatelow-vitamin B-12 interaction on serum holoTC and the metabolic markers of vitamin B-12 status is due to excess folic acid, an important consideration is at what level of exposure might these effects become metabolically and clinically relevant

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If a person is deficient due to insufficient B12, they may need to organize their diet to include more B12-rich foods or take an oral supplement

Among these formulations, F14 C2 was the most stable formulation with the remaining B 12 content of about 85.5%

However, it contains a cyanide molecule that the body must actively cleave off and detoxify before the B12 can be converted into a usable form

Am J Physiol Endocrinol Metab