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No changes in fasting glucose, insulin, HbA1c, IGF-1, cortisol, or thyroid hormones were detected at any dose tested

Solovyev, 2015)

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Thus, the interactive metabolic effects of high folatelow vitamin B-12 may occur at levels of exposure to folic acid that are regularly achieved in populations consuming folic-acidfortified foods and supplements

Knowing the guidelines for each helps healthcare providers tailor treatment