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4.3.2 System Xc - inhibition CS directly inhibits SLC7A11, the key subunit of System Xc -

Following the validation, the spectrofluorimetric assay method was utilized to determine glutathione content of rat livers

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Other studies showed that GR activates Nrf2 by stress response kinases (PI3K/AKT) ( The Nrf2 inducers have been a subject of many clinical trials, dimethyl fumarate (DMF) is now in clinical use to treat the skin disorder psoriasis (Robledinos-Antn et al., 2019)

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