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Lipocalin-2 plays an important role in RGC death and visual impairment via strongly promoting ferroptosis signaling (Mei et al., 2022)

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Malabsorption due to conditions that impair the bodys ability to absorb iron

The use of these proteins would be based on their expected biological activity: DSIP as the active peptide expected to induce sleep, and CBBBP to facilitate entry into brain

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elevated triglycerides (defined as 150 mg/dL), decreased High Density Lipoprotein (HDL) (ranges below 40 mg/dL in men and 50 mg/dL in women), elevated blood pressure (defined as systolic blood pressure above 130 mmHg or diastolic blood pressure above 85 mmHg) and elevated fasting glucose (defined as blood glucose above 100 mg/dL)