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Thus, understanding disease-specific astrocyte responses and targeting and modulating them presents an innovative treatment strategy for stroke and other neurological disorders

P1387 Cox T

10.1016/j.febslet.2015.02.012 134 SmithW

2.1.3 The -Syn phosphorylation Modifications of -Syn at the post-translational level (e.g., phosphorylation, ubiquitination, and nitration) can enhance its aggregation ability

Aberrant binding of HDACs at specific promoter regions suppresses normal functional gene transcription, inducing malignancy, such as promyelocytic leukemiaretinoic acid receptor- (PMLRAR) fusion proteins that reactivate HDACs and inhibit the expression of genes associated with hematopoietic cell differentiation, leading to the progression of acute promyelocytic leukemia (APL) 70

doi:10.1016/j.cofs.2014.07.001 Cingolani, P., Platts, A., Wang, L
