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Additionally, ASAH1 secretion into interstitial tissues facilitates tumor progression by modifying the surrounding microenvironment
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Dysregulation of this pathway leads to excessive cholesterol accumulation and contributes to hypercholesterolemia, a common feature of insulin resistance and metabolic syndrome
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SIRT2, present both in nuclear and cytoplasmic compartments, can increase MFN2 and decrease DRP1, thus promoting mitochondrial fusion 104,105
[DOI] [PubMed] [Google Scholar] 86.Lluis JM
