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Disadvantages of probes for the in vivo detection of redox reactive compounds may include artifactual amplification of the intensity by the formation of intermediate radicals, light sensitivity leading to artifactual H 2 O 2 generation, reaction with other reactive species, and interference/dependency of the reaction on enzymatic activity (Kalyanaraman et al., 2012)

Under oxidative stress conditions, FLSs exhibit abnormal proliferative capacity and invasive potential resembling tumor-like growth

Qiu P, Wang S, Liu M, Ma H, Zeng X, Zhang M, et al

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An early real life study reported greater day sleep duration after night shift when subjects left work early (6 am, before conflicting bright light) and took melatonin (5 mg) before day sleep (121)