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GFAP is an intermediate filament protein commonly used as a marker for astrocytes, which significantly increases in pathological-like states (e.g., aging and MS), indicating heightened astrocyte reactivity in rodents and humans (Nichols et al., 1993

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EGCG reduces amyloid beta (A) and tau toxicity and inhibits apoptosis in vitro and in a transgenic AD mouse model [48,49]

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