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A retrospective study in Argentina (20052023) involving over 54,000 men found that exposure to prolonged heatwaves during spermatogenesis led to significant reductions in sperm concentration, motility, and normal morphology (127)

Safety Studies Human growth hormone derivatives have raised concerns over risks such as insulin resistance, diabetes, acromegaly, cancer, hypertension, and edema (5)

The cellular mechanism involved in male infertility may provide new pathways for drug development from antioxidant compounds that are safe and secure and exert less toxic effects than commercially available classical drugs

PLoS ONE 12 , e0170517

Retrieved 17 April 2025

Balbas GM, Regana MS, Millet PU