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Structural and biochemical characterization of 20-hydroxysteroid dehydrogenase from Bifidobacterium adolescentis strain L2-32

However, mutant variants such as A53T bind to the lysosomal receptor LAMP2A but fail to translocate into the lumen, resulting in a blockage that impairs not only their own degradation but also that of other CMA substrates [171, 172]

[46] Moreover, in animal models of polymicrobial sepsis, semaglutide has been shown to decrease bacterial loads in multiple organs and promote the homeostasis of immunoregulatory regulatory T cells (Tregs) via the activation of FOXP3

Adult stem cells are mainly in a quiescence state and are constantly exposed to DNA-damaging agents