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In a previous study, p16 was found to be inactive in 85% of PC models, confirming the reliability of the above conclusions (217)

doi: 10.3791/53084 57 ParasaVRRahmanMJNgyuen HoangATSvenssonMBrighentiSLermM

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Nephrotoxic pathological changes are often caused by renal tubulointerstitial damage 5

Samples from human patients with high clinical scores and increased levels of cytokines and chemokines also contained significantly higher percentages of eicosanoid metabolites from the LOX and CYP pathways, including those derived from EPA and DHA, compared with healthy individuals