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The regulation of -GCS is complex

Additionally, elevated IGF-1 and IGF-1R levels can lead to increased cell growth, survival, and resistance to cell death, promoting tumor progression [96]

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280 Shank3 protein is a negative regulator of Parkin-mediated mitophagy and is enriched in the heart with increasing aging

The second line of antioxidant defense is represented by diet-derived antioxidants, including vitamins C and E, carotenoids, and flavonoids

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