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Ten Hoorn S, Elbers PW, Girbes AR, et al

GABA-edited MRS data were acquired with a modified MEGA-PRESS sequence (TE = 68 ms, TR = 1500 ms, 15ms editing pulses at 1.9/7.46 ppm for edit-ON/-OFF respectively, simple 2-step phase cycle to minimize periodic confounds, 700 transients total), from a 22 36 23 mm (18.2 mL) voxel placed medially in the Anterior Cingulate Cortex (ACC)

These findings are diagnostic of Klinefelter syndrome, caused by nondisjunction of X chromosome during meiosis

3,4 They also prevent oxidative stress, which occurs when there is an imbalance between free radicals and antioxidants, leading to cell and tissue damage

Subserosal Fibroids (FIGO 6 & 7): Because these grow on the outside of the uterus, they have more room to expand into the abdomen

This interaction prevented Annexin A2 from binding to the NF-B p50 subunit and their nuclear co-localization, thereby attenuating NF-B activation and downstream gene transcription (120)