wegovy glp-1 receptor agonist hydration effects 2025 POTD: and Ozempic — Maimonides Emergency Medicine Residency Medscape | Just over half

Long interested in Holst's work, in 1990 Novo Nordisk recruited his colleague Schwartz to develop small molecules able to activate the GLP receptor in the pancreas (Molteni, Chen)

Yuan Y, Yan Z, Lao Q, Jiang N, Wu S, Lu Q, et al

a figure that many patients on GLP-1 therapy fall short of, partly because the appetite suppression the medications produce makes hitting protein targets without conscious effort difficult. Clinical note Patients on GLP-1 therapy frequently report that protein-rich foods (particularly meat and eggs) become less palatable during treatment

L., John, L

Big Pharma couldn't care less as long as they're getting their payment

Considerable interest exists in identifying effects of these drugs beyond glucose-lowering, possibly resulting in improved macrovascular and microvascular outcomes, including in diabetic kidney disease