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489 Another statin, fluvastatin (NCT00416403), has measurable biological effects by reducing tumor proliferation and increasing apoptosis in breast cancer cells, with the effect being more pronounced in high-grade tumors

More patients have been diagnosed since the inclusion of lcFAODs in NBS panels, often before development of symptoms and it is debated whether dietary restrictions should be alleviated in certain patient groups [147, 148]

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Staging is not normally necessary in PDS

doi: 10.1186/1471-2490-13-53