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Stimulated by factors such as UV exposure, pollution, smoking, and poor diet, oxidative stress increases cellular aging and promotes the development of certain diseases

The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimers disease

During rapid weight loss, protein is the single most important macronutrient for preserving lean tissue
The skin's ability to produce vitamin D also decreases with age, so those over 65 years may require supplementation of Vitamin D

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