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This rapid clearance may help prevent the toxic accumulation of mediators in the bloodstream, significantly reducing the severity and duration of systemic MCAS flares, such as flushing, gastrointestinal distress, and neurological inflammation

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[DOI] [PubMed] [Google Scholar] 156.Coca-Pelaz A, Rodrigo JP, Shah JP, Sanabria A, Al Ghuzlan A, et al

SPP1 exacerbates ARDS via elevating Th17/Treg and M1/M2 ratios through suppression of ubiquitination-dependent HIF-1alpha degradation

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