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The nuclear factor erythroid 2-related factor 2 ( NFE2L2 or NRF2) transcription factor is constitutively activated in many cancers and promotes a specific gene expression program involved in cellular detoxification, redox buffering, and metabolic rewiring (Cancer Genome Atlas Research, 2012

N-acetylcysteine Hynninen MS, Niemi TT, P, Raininko EI, SalmenperT, Lepalo MJ, Railo MJ, Tallgren MK

To substantiate the role of GSH in ABCC1-mediated resistance, cells were preincubated with buthionine-sulfoximine (BSO) (1 M, 18 h) prior to DpC treatment

Detoxification Support One of glutathione's key roles is assisting the liver in detoxifying harmful substances

It's like giving your liver a complete toolkit instead of just one tool

To ensure you're getting optimal glutathione benefits and maintaining healthy levels, you can take them together