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VIC can be accumulated in different tissues (e.g., brain, liver, skeletal muscles, corneal epithelium, neutrophile, stem cells) via specific transporters, and it can enhance cellular functions [5,6,7,8]
Rechallenge with ABC should however, never be pursued after a hypersensitivity reaction
In a phase 1 safety trial, GDNF delivered directly into patients putamen (Fig
Zdimerova H, Murer A, Engelmann C, Raykova A, Deng Y, Gujer C, et al
