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However, because they have no anti-inflammatory properties (but have the potential to mask inflammatory symptoms), they should always be used in combination with an anti-inflammatory corticosteroid in order to reduce the risk of a potentially fatal asthma attack resulting from uncontrolled tissue inflammation (see BLACK BOX WARNING)

activation is then triggered by diverse microbial or sterile stimuli and is typically accompanied by potassium (K + ) efflux and other ionic changes [91]

Continuous Use There is limited research on optimal cycling strategies (periods of use followed by breaks) versus continuous use
Never exceed conservative dosing: Doses above 5060 mcg/day lack robust clinical research support and may substantially increase adverse effect risk [2]

10.1016/j.cell.2020.08.007 70 MatsuokaK.KanaiT
