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Moreover, iron-related biomarkers hold potential for treatment response prediction and therapeutic monitoring

Intervention Strategies: Anti-VEGF neutralizing antibodies (e.g., bevacizumab/B20) or anti-angiogenic tyrosine kinase inhibitors (e.g., axitinib), by blocking VEGF signaling, not only reduce pathological angiogenesis, edema, and hemorrhage but also decrease peripheral nerve density mediated by the interaction of VEGF with neuropilin (NRP), thereby alleviating pain

Diosgenin, a major biologically active natural steroidal sapogenin found in Chinese yam, has been widely reported as a therapeutic agent in the treatment of various classes of disorders such as hyperlipidemia, inflammation, diabetes, cancer, infection, and immunoregulation

Adiaspiromycosis: an unusual fungal infection of the lung

Neuro-Oncol Adv

Given the theoretical concern about angiogenesis and cancer, one might expect at least some reports of unexpected tumor development if the risk were significant