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4-Hydroxypanduratin A and Isopanduratin A Inhibit Tumor Necrosis Factor -Stimulated Gene Expression and the Nuclear Factor B-Dependent Signaling Pathway in Human Lung Adenocarcinoma A549 Cells

Long-term Storage: Store at -20C in a desiccated, moisture-free environment

Higenamine, an aporphine alkaloid, reduced MMP-1 expression, an enzyme associated with collagen degradation, by inhibiting AP-1 and NF-B transcription factors, and it decreased oxidative stress-related kinase phosphorylation, lowering ROS levels in HaCaT cells [104]

Additionally, cranberry extract also reduces the appearance of fine lines, providing incredible wrinkle reduction benefits

Its stability in the digestive environment also allows it to be effective when taken orally, making it well-suited for gut-focused protocols