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Charkoudian N, Johnson JM
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EMBO Mol Med 15:EMMM202217052-
When it comes to 1-MNAM, an often-overlooked product of vitamin B3 elimination, a newly published study found that 1-MNAM secreted by NNMT-expressing tumor cells was elevated in T cells and induced T cells to secrete the tumor-promoting cytokine tumor necrosis factor (TNF) in human ovarian cancer [52]
