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Hydroxylation of MG to form 7-HMG markedly increased hMOR affinity, which our models attribute to the formation of a direct hydrogen bond with ASN124 (3.1 ), consistent with previous proposals that polar contacts at this residue enhance agonist potency (Huang et al., 2015

John Wiley & Sons

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These intervals assume a conservative at-home session at a shallow fixed depth

A phase II study of the efficacy and safety of the MET inhibitor capmatinib (INC280) in patients with advanced hepatocellular carcinoma
Mol Aspects Med 2018;62:75-88
