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For the theophylline example given in the Box, Example: Maintenance Dose Calculations, the loading dose would be 350 mg (35 L 10 mg/L) for a 70-kg person
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The Nomination, Evaluation, and Voting Process The final 503A Bulk Drug Substance List is in current development

Preventing Hypothermia Hypothermia occurs when the bodys warming mechanisms fail and the body temperature drops below 35C

doi: 10.1016/j.dci.2009.08.010 257 LiuJYangWLiaoWHuangYChenWBuXet al
