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[DOI] [PubMed] [Google Scholar] Park, S.O

Glutathione, also referred to as GSH, is a tripeptide composed of three amino acids: cysteine, glycine, and glutamic acid

The crosstalk between the folate and methionine cycles goes beyond the re-methylation of homocysteine, as de novo ATP synthesis powered by the folate cycle directly contributes to the formation of SAM, a critical donor to multiple methylation reactions (Maddocks et al., de novo generation of ATP by the folate cycle is likely to be indispensable in maintaining energetic homeostasis, particularly in conditions of high energy demand such as sustaining high rates of proliferation

It is a temporary intervention, not a long-term dietary plan

However, the team noted a confounding factor in the effectiveness analysis: during the study, four patients started treatment with cystic fibrosis transmembrane conductance regulator (CFTR) modulators

This multifarious function of lncRNAs with regard to chromatin remodeling and stress responses raises much hope for using lncRNAs as targets in emerging crop varieties that can resist stress, in light of the avenues it opens up for agricultural innovation in climate change scenarios (Yang et al., 2023)
