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[17] In contrast, supplementation with glutathione is incapable of increasing cellular glutathione since the GSH concentration found in the extracellular environment is much lower than that found intracellularly by about a thousand-fold

doi: 10.1371/journal.pbio.2006203 45 SongXLongD

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During the NASH stage, over activated autophagy can lead to extensive hepatocyte death, further aggravating liver inflammation and fibrosis [106]

Vargas MR, Johnson DA, Johnson JA (2011) Decreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1(G93A) mice model

To view a copy of this licence, visit About this article Cite this article Hashimoto, S., Matsuba, Y., Takahashi, M