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Using stable isotope-resolved metabolomics (SIRM) studies [49], Le et al
SFN functions by inhibiting and enhancing phase I enzymes interacting with cytochrome P450 and phase II enzymes by activating Nrf2 (Nuclear factor E2-factor related factor) (96) (Figure 2)
Staines, D
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In contrast, S6, S7, S8, and S9 showed overlapping PCA distributions, suggesting comparable metabolite profiles, which was further confirmed by hierarchical cluster analysis (Figure 6)
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