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Notably, apoptotic cell-derived metabolites and products (such as methionine [163], arginine [164], and DNA [73]) play vital roles in the efferocytosis-mediated resolution of inflammation [165] (Fig

In particular, low Treg numbers or Treg dysfunction aggravates autoimmune activity and results in SLE development

These changes were mirrored by changes in the lung (Figure 5A) and liver (Figure 5B) tissue GCL activity which is a good indicator of a tissue's capacity to maintain GSH levels

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Thus, downregulation improves the response speed of the EGFR signaling and contributes to better information processing and faster adaptation

Incorporating immune and stromal cell into co-culture systems increases their biological significance, while OOC platforms and bioprinting technologies replicate dynamic physiological settings, facilitating HTS drug screening and tailored therapeutic approaches