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More relevant to our present findings, Cersosimo et al

Much of the energy production of the body goes into fueling neurons, which have a high rate of energy expenditure (Box 2)

The epithelium of the non-inflamed ileum shows a normal permeability to ions and a normal paracellular permeability to 51 Cr-EDTA as compared to controls (119, 120) but is more susceptible to a challenge with sodium caprate indicating that TJs in the non-inflamed ileum of CD are more reactive to luminal stimuli contributing to the development of mucosal inflammation (120)

This is incredibly important, especially for detoxification

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