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Reserve stores of B12 can become depleted due to poor dietary intake without supplementation, lack ofintrinsic factor, or poor intestinal absorption

Also, its listed as prohibited by WADA (World Anti-Doping Agency)

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If your vitamin B12 levels are too high on the serum vitamin B12 test, your doctor may recommend further testing

A deficiency can also cause a condition called megaloblastic anemia which creates larger, immature, and abnormal red blood cells and leads to impaired DNA synthesis

Researchers and biohackers alike have explored its application for accelerating the healing of soft tissues including tendons, ligaments, muscles, skin, blood vessels, and even nerves