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In biological function, this rigid extension may function as a molecular scaffold or arm, fully exposing and extending the C-terminal RGD motif beyond the bacterial surface

10.1038/s41588-023-01335-9 159 QianJ.LiuJ.HongL.LuH.GuoD.LiuZ.et al (2020)

3 Fentanyl, a highly potent synthetic opioid, has been identified as a driver of overdose deaths involving other opioids, benzodiazepines, alcohol, methamphetamine, and cocaine

Renal, Liver, and Heart Histology The same scoring system as in the previous studies [12,13,14,15,16,20,22,23,24] was used to grade renal (i.e., the degeneration of Bowmans space and glomeruli, degeneration of the proximal and distal tubules, vascular congestion, and interstitial edema), liver (i.e., vacuolization of hepatocytes and pyknotic hepatocyte nuclei, activation of Kupffer cells, and enlargement of sinusoids) and heart (i.e., dilatation and congestion of blood vessels within the myocardium and coronary arteries) histology

H3K18la, H4K15la and protein Kla directly fuel this hyper-proliferative phenotype

(2022b, December 8)