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HIV-1 Tat-mediated microglial activation by impairing mitophagy/autophagy Mitophagy selectively removes damaged mitochondria through a progression from phagophore to autophagosome and then to lysosome, thereby preserving organelle integrity and cellular homeostasis [82]

3.4 Multiple sclerosis Multiple sclerosis (MS) is a chronic autoimmune disease that affects the CNS

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Atractylodin attenuates dextran sulfate sodium-induced colitis by alleviating gut microbiota dysbiosis and inhibiting inflammatory response through the MAPK pathway

BPC-157 is a pentadecapeptide consisting of 15 amino acids derived from a biologically active region of a gastric protein sequence, while TB-500 corresponds to a synthetic fragment of thymosin beta-4 that retains actin-binding regulatory activity observed in the native protein