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This may directly or indirectly lead to cerebral dysfunction, e.g., by inducing reperfusion injury, lactate production, BBB disruption, cerebral edema, ROS-production, activation of the Nod-like receptor family pyrin domain-containing 3 (NLRP3)-inflammasome or other processes that induce glial reactivity and aggravate CNS inflammation (for details, see section Abnormal CBF)

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[118] Three weeks later against the Panthers, he caught five passes for 41 receiving yards and threw an interception in a 1610 loss