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Coller, H.A., "Is cancer a metabolic disease?", American Journal of Pathology 184 (1): 4-17 (2014)

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Another study revealed that the mRNA levels of proinflammatory markers (IL-1, IL-6, TNF-, and lymphotoxin A) and anti-inflammatory markers (cytokine IL-10, and of IL-1 receptor antagonist (IL-1RA)) were substantially increased and decreased, respectively, in the prefrontal cortex of depressed individuals who committed suicide [67]

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As such, it can recognize key allosteric communication residue players (Rapisardi et al

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When accumulated nanoparticles detect high levels of ROS in the TME, the therapeutic drug is released, which is more precise and efficient [68]

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