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REDEFINE 1: Strong Results, Missed Ambitions The first pivotal trial, REDEFINE 1, enrolled 3,417 adults with obesity or overweight and at least one weight-related comorbidity, but without type 2 diabetes
10.1152/ajplegacy.1975.229.3.770 20 BecharaA.BerridgeK
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132 In a recent study of children with HIV, a daily supplement of vitamins A, B complex, C, D, E, and folic acid, plus zinc, iron, and copper (at levels based on recommended daily allowances) corresponded with faster recovery from diarrheal episodes and pneumonia
A number of recent investigations of the control of cell fate by mitophagy have enhanced our understanding of the mechanisms by which mitophagy regulates ototoxicity and other hearing-related diseases, providing opportunities for targeting mitochondria to treat ototoxicity
A mathematical model of the folate cycle: new insights into folate homeostasis
