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Collectively, these findings highlight the pivotal role of the myelin sheath in coordinating neuronal survival, communication, and synaptic functions
Elevated cardiac ferroptosis markers in heart failure patients with diabetes Decreased myocardial GPX4 expression and activity in diabetic heart failure patients According to guidelines for evaluating myocardial cell death, diminished expression of glutathione peroxidase-4 (GPX4), a lipid-specific antioxidant, serves as a pivotal indicator of ferroptosis [15]
PMID 17182618
The most important compartments for redox signaling in pancreatic -cells are the mitochondria, the cytoplasm with the plasma membrane rafts, while oxidation in ER with the Golgi apparatus has more structural functions
References 1.D.-W
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