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(6) Cholinergic crisis: Excess dosing may result in severe muscle weakness and respiratory compromise, requiring urgent recognition and discontinuation of therapy

Dehydroascorbate-reducing proteins in maize are induced by the ascorbate biosynthesis inhibitor lycorine. Plant Physiol

Participants will take either the study drug or a placebo for 12 weeks, with the option to continue treatment for up to 64 weeks

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NADPH: reduced nicotinamide adenin dinucleotide phosphate

The position of the ATP -phosphate is mimicked by the phosphoryl group of the Gsp analogue