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We will also provide guidance on follow-up treatments, potential side effects, and any lifestyle recommendations to complement your care

Many patients taking GLP-1 medications like semaglutide ask whether adding B12 supplementation is necessary or safe

Administered regularly, B-12 may accelerate weight loss by offering an energy boost that can promote physical activity and muscle strength

The goal is to introduce the water as gently as possible

Always consult your prescribing clinician before combining supplements with your medication, and monitor energy and gastrointestinal tolerability over the first 2 to 3 weeks

Finally, none of these studies included intention-to-treat analysis, blinding or sample size calculation, which may have introduced bias in their statistical analysis (Vidal-Alaball et al., 2004