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This combination contributes to improved glucose control and weight loss

The evidence base for tirzepatide as monotherapy is robust, with pivotal trials including SURMOUNT-1 demonstrating significant weight reduction in adults with obesity, and SURPASS trials establishing glycemic efficacy in type 2 diabetes

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doi: 10.1046/j.1467-789x.2001.00040.x

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Since B12 is water-soluble, it can be absorbed directly into your bloodstream, especially when administered via an IV