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In the absence of light, BSO and Ce6 combination did not practically increase reactive oxygen species (ROS) in either of HCT116 or SNU478 cells, while light irradiation increased ROS level dose-dependently

Competitive Displacement: FOXO4-DRI mimics the binding site of FOXO4. It binds to p53 with high affinity, displacing the endogenous FOXO4

1, July 2005, pp