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Description
Larazotide works complementarily by binding claudin receptors to restore the tight-junction barriers that, when compromised, allow bacterial endotoxins from periodontal pathogens to penetrate systemic circulation
C.Zijlstra-WillemsE
Biochim Biophys Acta, 2010
Malignant cells within a solid tumor rapidly proliferate and organize, which can lead to poor vascularization that exacerbates TME hypoxia

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It's also worth noting that although Gln can be decomposed to Glu catalyzed by the glutaminases GLS1 and GLS2, only the catalysis of the latter is associated with ferroptosis (Gao et al
